Search results for " Claudi"
showing 10 items of 50 documents
Peripheral artery disease, redox signaling, oxidative stress – Basic and clinical aspects
2017
Reactive oxygen and nitrogen species (ROS and RNS, e.g. H2O2, nitric oxide) confer redox regulation of essential cellular signaling pathways such as cell differentiation, proliferation, migration and apoptosis. At higher concentrations, ROS and RNS lead to oxidative stress and oxidative damage of biomolecules (e.g. via formation of peroxynitrite, fenton chemistry). Peripheral artery disease (PAD) is characterized by severe ischemic conditions in the periphery leading to intermittent claudication and critical limb ischemia (end stage). It is well known that redox biology and oxidative stress play an important role in this setting. We here discuss the major pathways of oxidative stress and re…
Clinical analysis following lumbar interspinous devices implant: where we are and where we go
2014
Objectives:We present our experience with patients treated with interspinous devices who are affected by neurogenic intermittent claudication (NIC) or lumbar disc herniation (LDH) where the interspinous system has been inserted following microdiscectomy.Study design:Retrospective study.Methods:This study included patients (n=100) with NIC secondary to lumbar spinal stenosis (group 1), and patients (n=100) with LDH (group 2) in whom the interspinous device has been implanted following radicular decompression in a period spanning 6 years. The latter have been compared with a homogenous group of patients (n=100) where no interspinous system has been implanted following microdiscectomy (group 3…
One-year results from the DETOUR I trial of the PQ Bypass DETOUR System for percutaneous femoropopliteal bypass
2019
The objective of this study was to evaluate the 1-year safety and effectiveness outcomes associated with the PQ Bypass DETOUR System (PQ Bypass, Milpitas, Calif) for the percutaneous bypass of long-segment femoropopliteal occlusive disease.This prospective, single-arm, multicenter trial enrolled patients with long-segment femoropopliteal arterial disease. The DETOUR System percutaneously deploys modular stent grafts to bypass femoropopliteal lesions through a transvenous route. Eligible patients included those with TransAtlantic Inter-Society Consensus C and D lesions100 mm in length. The primary safety end point was the major adverse event (MAE) rate through 1 month, defined as the composi…
The Effects of Prostaglandin E-1 in Patients with Intermittent Claudication
2006
Aim of the study is to evaluate the effects of Prostaglandin E-1 (PGE-1) in patients with peripheral arterial disease (PAD) at the 2nd b stage Fontaines classification. The study, controlled, single blinded, enrolled 123 patients with intermittent claudication that were randomised in two groups; the first group received a treatment with PGE-1 while the second one received a pentoxifylline-buflomedil association by venous infusion. We evaluated: Pain Free Walking Distance (PFWD), Maximum Walking Distance (MWD), Rest Flow (RF), Peak Flow (PF), Basal (BVR) and Minimal Vascular Resistance (MVR) with a strain gauge plethysmograph, Resting Flow (RF), Peak Flow (PF), time to reach the Peak Flow (t…
Historical and Technical Notes on Aqueducts from Prehistoric to Medieval Times
2013
The aim of this paper is to present the evolution of aqueduct technologies through the millennia, from prehistoric to medieval times. These hydraulic works were used by several civilizations to collect water from springs and to transport it to settlements, sanctuaries and other targets. Several civilizations, in China and the Americas, developed water transport systems independently, and brought these to high levels of sophistication. For the Mediterranean civilizations, one of the salient characteristics of cultural development, since the Minoan Era (ca. 3200-1100 BC), is the architectural and hydraulic function of aqueducts used for the water supply in palaces and other settlements. The M…
Cien años de arqueología funeraria en el estrecho de Gibraltar: Nuevas investigaciones en la necrópolis de Baelo Claudia (Tarifa, Cádiz)
2014
En este trabajo abordamos el estudio de la necrópolis oriental de Baelo Claudia (Tarifa, Cádiz) a partir de los trabajos arqueológicos y de interpretación de las antiguas intervenciones que llevamos a cabo desde la Universidad de Alicante. Asimismo, junto con los resultados de la última excavación, se plantean nuevas lecturas sobre el paisaje funerario, la religiosidad y la etnicidad, así como sobre la tipología monumental y los ajuares. The new archaeological research conducted by University of Alicante in the Eastern necropolis of Baelo Claudia (Tarifa, Cádiz) are presented in this paper. Drawing on renewed reinterpretations of ancient excavations which have been enriched with the results…
Leukocyte–platelet aggregates—a phenotypic characterization of different stages of peripheral arterial disease
2016
The formation of monocyte-platelet aggregates and neutrophil-platelet aggregates (MPA and NPA, respectively) is influenced by inflammation, but also might contribute to an exacerbation of inflammatory responses in atherosclerotic plaque. The purpose of this study was to analyze MPA and NPA proportions in regard to different stages of peripheral arterial disease (PAD). Forty-five patients with intermittent claudication (IC) (3 groups: Rutherford (R)-1, R-2, and R-3; each n = 15), 20 patients with critical limb ischemia (CLI) (Rutherford 5 (40%) and 6 (60%)), and 20 healthy controls were studied. Analyses of monocyte (Mon) subpopulations (CD14++CD16- (classical) Mon1, CD14++CD16+ (intermediat…
Estudios del botánico aragonés Ignacio Jordán de Asso en la Universidad de Zaragoza (1760-1763)
2017
Este artículo se encuentra disponible a texto completo en la siguiente URL: http://www.floramontiberica.org/FM/Flora_Montiberica67.pdf Se hace un somero repaso biográfico de Ignacio Jordán de Asso, destacando la importancia de sus obras botánicas, precisando los años que cursó en la Universidad de Zaragoza sus estudios de Leyes y el ambiente académico de la época. / Ignacio Jordán de Asso’s quick biographical review, emphasizing the importance of his botanical works, specifying the school years in the University of Zaragoza studing Laws and the study environment of the period.
Consensus Document on Intermittent Claudication from the Central European Vascular Forum (C.E.V.F.)-3rd revision (2013) with the sharing of the Medit…
2014
This paper is the review of the Consensus Document on Intermittent Claudication of the Central European Vascular Forum (CEVF), published in 2008, and and shared with the North Africa and Middle East Chapter of International Union of Angiology and the Mediterranean League of Angiology and Vascular Surgery. The Document presents suggestions for general practitioners and vascular specialists for more precise and appropriate management of PAD, particularly of intermittent claudication, and underlines the investigations that should be required by GPs and what the GP should expect from the vascular specialist (angiologist, vascular surgeon). The idea of the Faculty is to produce a short document,…
Esse.Re (nel) mondo. Arti visive e rinascita dal 1966 a oggi
2022
Nel complesso quadro distopico della pandemia il saggio prende in esame il progetto espositivo e curatoriale .RE, mostra che non si limita a presentare le ricerche di una selezione di artisti tra i più influenti dei nostri tempi ma si focalizza sull’urgente necessità di problematizzare le dicotomie arte/vita, azione/contemplazione, arte/anti-arte, nella prospettiva di una riflessione critica intorno a una raccolta di opere innovative, tanto nel metodo quanto nel contenuto. Vengono esaminate le opere più significative delle ricerche condotte da Alberto Burri, Saint Clair Cemin, Tony Cragg, Zang Hong Mei, Anselm Kiefer, Jeff Koons, Sol LeWitt, Emil Lukas, Mimmo Paladino, Claudio Parmiggiani, …